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Pacific Biosciences of California, Inc.
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$880M
Market Cap
—
P/E
—
PEG
-19.5%
ROCE
—
ROE
—
D/E
-111.5%
OPM
0.0%
% from 52W High
97
α RS
🌏 Global Investor Returns
Currency-adjusted total returns for PACB including FX impact
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📈 Price History
Ratio Health
— Excellent
— Good
— Average
— Poor
By Category
📊 Peer Medians
About

Pacific Biosciences of California, Inc. designs, develops, and manufactures sequencing solutions to resolve genetically complex problems. The company provides sequencing systems; consumable products, including single molecule real-time (SMRT) technology; long-read sequencing; and various reagent kits designed for specific workflow, such as preparation kit to convert DNA into SMRTbell double-stranded DNA library formats, including molecular biology reagents, such as ligase, buffers, and exonucleases. It also offers binding kits, such as modified DNA polymerase used to bind SMRTbell libraries to the polymerase in preparation for sequencing; and sequencing kits comprise reagents required for on-instrument, real-time sequencing, including the phospholinked nucleotides. In addition, the company provides Revio, Vega, and Sequel instruments which conduct, monitor, and analyze single-molecule biochemical reactions on SMRT cell microchips; short-read sequencing; and onso instrument. It serves academic and governmental research institutions, commercial testing and service laboratories, genome centers, public health labs, hospitals and clinical research institutes, contract research organizations, pharmaceutical companies, and agricultural companies. The company markets its products through a sales force and distribution partners in Australia, certain parts of Asia, Europe, the Middle East, Africa, Central America, and South America. It has a collaboration with DNAstack Inc. to provide federated dataset of HiFi whole genome sequencing data. The company was formerly known as Nanofluidics, Inc. and changed its name to Pacific Biosciences of California, Inc. in 2005. Pacific Biosciences of California, Inc. was incorporated in 2000 and is headquartered in Menlo Park, California.

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⭐ Superinvestors Holding PACB
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Manager Shares Value % of Fund Period
Cathie Wood ARK Investment Management 36.27M $47.9M 0.37% Mar 2026
Jim Simons Renaissance Technologies LLC 2.49M $3.3M 0.01% Mar 2026
Steve Cohen Point72 Asset Management 285.7K $377K 0.00% Mar 2026

SEC Form 13F data. 45-day lag from quarter end.

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✓ 📞 Earnings Call Transcripts (5 quarters) submit a missing quarter
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📞 Earnings Call Transcripts (5)
Q2 2026 Q2 2026 2026-08-05
Leadership transitioned to Mark Van Oene as CEO, with a strategic focus on clinical market expansion and operational efficiency. Q2 revenue was $39 million, flat year-over-year, with strong clinical adoption but ongoing funding and cost headwinds. 2026 guidance was lowered, and cash flow breakeven is now expected in 2028.
Q1 2026 Q1 2026 2026-05-07
Record consumable revenue and strong clinical adoption offset weaker instrument sales due to funding pressures. Guidance for 2026 was lowered, but consumables and new product launches are expected to drive growth, with EMEA leading regional performance.
Q4 2025 Q4 2025 2026-02-12
Q4 and full year 2025 saw record consumable revenue and strong instrument placements, with clinical adoption driving growth despite academic funding headwinds. 2026 guidance projects 8% revenue growth, margin expansion, and continued focus on long-read sequencing and cost discipline.
Q3 2025 Q3 2025 2025-11-05
Q3 2025 revenue was $38.4M, with record consumables driving gross margin to 42%. EMEA led growth, while Americas and Asia-Pacific faced funding headwinds. Full-year revenue guidance narrowed to $155–$160M, with strong clinical momentum and new product launches supporting long-term growth.
Q2 2025 Q2 2025 2025-08-07
Q2 2025 saw 10% year-over-year revenue growth, driven by strong international demand and robust consumables sales, while U.S. academic funding headwinds persisted. Guidance for 2025 was narrowed, with improved gross margin expectations and continued cost discipline supporting a path to positive cash flow by 2027.
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📊 Analysis Methodology

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Financial Model
Projections are built from each company's audited annual financials (Income Statement, Balance Sheet, Cash Flow) over the last 5 fiscal years. Forward assumptions — revenue growth %, EBITDA margin, D&A (USD millions), interest expense, tax rate, and capex — are AI-generated using historical context and refreshed twice a year: after the December results season and after the September/Q4 results season.

DCF Valuation
Fair Value = Σ(FCFt / (1+WACC)t) + Terminal Value. Terminal Value uses the Gordon Growth Model: FCF5 × (1+g) / (WACC−g). Default WACC: 10% (US risk-free ~4.5%, equity risk premium ~5.5%). Default terminal growth: 3% (long-run US nominal GDP proxy).

CAGR Tracker
Expected 5-year CAGR = (DCF Fair Value / Current Price)1/5 − 1. Assumes fair value is reached in exactly 5 years — a mechanical estimate only.

Data Sources & Limitations
Financial statements sourced from public filings. Prices updated daily. Forward assumptions are AI-generated. All monetary values in USD millions. Non-US ADR companies may have currency conversion inaccuracies. Models are point-in-time and do not update intra-quarter or account for M&A, macro shocks, or extraordinary items.

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Investment Risk:
Investing in securities, including US equities and ETFs, involves inherent risks including the potential loss of principal. All investments are subject to market fluctuations, economic conditions, regulatory changes, and other factors that may affect their value. Past performance is not indicative of future results. This analysis is provided for informational and educational purposes only and should not be construed as investment advice under any circumstances.

No Investment Recommendation:
This analysis does not constitute, nor should it be interpreted as, an offer, solicitation, or recommendation to buy, sell, or hold any securities or financial products. Investors are strongly advised to conduct their own independent research and due diligence and to consult with a licensed financial advisor or an SEC-registered investment adviser before making any investment decisions, taking into account their individual financial situation, risk tolerance, and investment objectives.

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Conflict of Interest Disclosure:
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Information Sources:
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