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Personalis, Inc.
🏹 Trader: 🚀 Stage 2 + Near High 📈 Stage 2 🎯 Near 52W High | BRS 77 Ready View all →
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$1.5B
Market Cap
P/E
PEG
-166.3%
ROCE
-35.0%
ROE
0.17
D/E
-126.4%
OPM
-11.8%
% from 52W High
97
α RS
🔍 PSNL is showing a high-conviction setup because it matches 3 of 39 tracked screener presets, RS Rating is 97 (top decile vs market), and it's within 11.8% of its 52-week high. Net: Broad signal stack, not a recommendation. ? Conviction RS Rating 52W High
Sources
Conviction 3/39 · RS Rating 97 · 11.8% from 52W high
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📈 Price History
Ratio Health
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By Category
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About

Personalis, Inc. develops, markets, and sells advanced cancer genomic tests and services in the United States and internationally. The company offers NeXT Personal, a tumor-informed liquid biopsy test for detection of minimal residual disease (MRD), therapy response and recurrence monitoring in solid tumor cancers; and ImmunoID NeXT, a tissue-based service that combines whole exome and whole transcriptome sequencing data with advanced analytics to provide a multi-dimensional view of the tumor and the tumor microenvironment from a single sample. It also provides NeXT Personal Dx, a tumor-informed liquid biopsy test for the detection of MRD; and NeXT Dx, a tumor profiling test that is used to help select therapy for a cancer patient and identify potential clinical trials for a patient. In addition, the company performs whole exome sequencing of cancer tissue and matched blood samples for diagnostic companies as an input to their products; and whole genome sequencing on human samples for research projects, such as population sequencing initiatives. Its services are used by pharmaceutical companies for translational research, biomarker discovery, the development of personalized cancer therapies, and for clinical trials, as well as tests are used by physicians to detect residual or recurrent cancer in patients, monitor cancer response to therapy, and uncover insights for therapy selection. The company’s customers include pharmaceutical companies, biopharmaceutical companies, diagnostics companies, universities, non-profits, government entities, and cancer patients. The company has strategic collaboration with Tempus AI, Inc. to bring testing to colorectal cancer patients. Personalis, Inc. was incorporated in 2011 and is headquartered in Fremont, California.

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📈 Growth Pattern
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⭐ Superinvestors Holding PSNL
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Manager Shares Value % of Fund Period
Cathie Wood ARK Investment Management 7.94M $50.6M 0.39% Mar 2026
Jim Simons Renaissance Technologies LLC 15.2K $97K 0.00% Mar 2026

SEC Form 13F data. 45-day lag from quarter end.

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✓ 📞 Earnings Call Transcripts (5 quarters) submit a missing quarter
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📞 Earnings Call Transcripts (5)
Q1 2026 Q1 2026 2026-05-07
Clinical test volumes surged 26% sequentially and 258% year-over-year, with Q1 revenue at $15.5M and strong physician adoption. Gross margin compressed to 1.8% due to strategic investments, but full-year guidance of $78–$80M is reaffirmed, with margin improvement expected in H2.
Q4 2025 Q4 2025 2026-02-26
Explosive clinical test growth and two Medicare coverage wins drove momentum in 2025, with 2026 guidance targeting $78–$80 million revenue and 43,000–45,000 clinical tests. Margin compression is expected to persist until further reimbursement, but strong cash reserves support aggressive expansion.
Q3 2025 Q3 2025 2025-11-04
Q3 saw 4,388 clinical tests (up 26% sequentially, 364% year-over-year) and $14.5M revenue, with strong MRD adoption and three MolDX dossiers under review. Guidance was revised lower due to biopharma timing and reimbursement delays, but cash discipline remains strong.
Q2 2025 Q2 2025 2025-08-05
Q2 2025 featured strong clinical growth and expanding physician adoption, but revenue declined 24% year-over-year due to biopharma project delays. Full-year guidance was lowered to $70M–$80M, with Medicare reimbursement for NeXT Personal expected to be a major catalyst.
Q1 2025 Q1 2025 2025-05-06
Q1 2025 revenue grew 6% year-over-year to $20.6M, with biopharma revenue up 39% and strong MRD test adoption. Guidance for 2025 is $80M-$90M revenue, with investments focused on clinical volume and reimbursement for at least two indications. Cash position remains strong at $185.7M.
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Financial Model
Projections are built from each company's audited annual financials (Income Statement, Balance Sheet, Cash Flow) over the last 5 fiscal years. Forward assumptions — revenue growth %, EBITDA margin, D&A (USD millions), interest expense, tax rate, and capex — are AI-generated using historical context and refreshed twice a year: after the December results season and after the September/Q4 results season.

DCF Valuation
Fair Value = Σ(FCFt / (1+WACC)t) + Terminal Value. Terminal Value uses the Gordon Growth Model: FCF5 × (1+g) / (WACC−g). Default WACC: 10% (US risk-free ~4.5%, equity risk premium ~5.5%). Default terminal growth: 3% (long-run US nominal GDP proxy).

CAGR Tracker
Expected 5-year CAGR = (DCF Fair Value / Current Price)1/5 − 1. Assumes fair value is reached in exactly 5 years — a mechanical estimate only.

Data Sources & Limitations
Financial statements sourced from public filings. Prices updated daily. Forward assumptions are AI-generated. All monetary values in USD millions. Non-US ADR companies may have currency conversion inaccuracies. Models are point-in-time and do not update intra-quarter or account for M&A, macro shocks, or extraordinary items.

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Information Sources:
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